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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1447845
Molecular formula	C21H21F3N6O4
IUPAC name	[3-(trifluoromethyl)oxetan-3-yl] (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
Molecular weight	478.432
Hydrogen bond acceptor	12
Hydrogen bond donor	0
XlogP	1.5
Synonyms	CHEMBL3220237 4-[5-(3-Cyanopyridine-4-ylmethoxy)pyrimidine-2-yl]-5alpha-methylpiperazine-1-carboxylic acid 3-(trifluoromethyl)oxetane-3-yl ester
Inchi Key	GFSWORTTYOAWML-CQSZACIVSA-N
Inchi ID	InChI=1S/C21H21F3N6O4/c1-14-10-29(19(31)34-20(12-32-13-20)21(22,23)24)4-5-30(14)18-27-8-17(9-28-18)33-11-15-2-3-26-7-16(15)6-25/h2-3,7-9,14H,4-5,10-13H2,1H3/t14-/m1/s1
PubChem CID	58190317
ChEMBL	CHEMBL3220237
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
95356	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
95357	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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