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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL430122
Molecular formula	C27H32N6O2
IUPAC name	4-(5-cyano-1H-indol-3-yl)-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]piperidine-1-carboxamide
Molecular weight	472.593
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.1
Synonyms	BDBM50086100 N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-4-(5-cyano-1H-indole-3-yl)piperidine-1-carboxamide 4-(5-Cyano-1H-indol-3-yl)-piperidine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide SCHEMBL6357223
Inchi Key	GJIIWFJJJBJFMX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32N6O2/c1-31-11-13-32(14-12-31)25-16-21(4-6-26(25)35-2)30-27(34)33-9-7-20(8-10-33)23-18-29-24-5-3-19(17-28)15-22(23)24/h3-6,15-16,18,20,29H,7-14H2,1-2H3,(H,30,34)
PubChem CID	10838188
ChEMBL	CHEMBL430122
IUPHAR	N/A
BindingDB	50086100
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
97933	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
97934	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
97935	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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