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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LY 344864 racemate
Molecular formula	C21H22FN3O
IUPAC name	N-[6-(dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide
Molecular weight	351.425
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.8
Synonyms	186543-64-6 CS-0022633 LY344864 GTPL21 NCGC00167736-01 CAS_5311097 PDSP2_001556 D0O9TT LY344864 racemate HCl BCP23551 HY-13788C NSC_5311097 CHEMBL3186179 LY-344864 SCHEMBL7665368 6-(4-fluorobenzoyl)amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole GKWHICIUSVVNGX-UHFFFAOYSA-N N-(6-dimethylamino-6,7,8,9-tetrahydro-5H-carbazol-3-yl)-4-fluorobenzamide BDBM85195 L000365 PDSP1_001572 [ Show all ]
Inchi Key	GKWHICIUSVVNGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22FN3O/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26)
PubChem CID	18971832
ChEMBL	N/A
IUPHAR	21
BindingDB	85195
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99068	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
99075	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
99069	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
99072	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
99070	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
99066	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
99067	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
99076	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
99065	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
99078	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
99071	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
460107	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
99073	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
555841	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
99074	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
99077	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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