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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL333519
Molecular formula	C8H10FNO4
IUPAC name	(1R,2S,5R,6R)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	203.169
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.0
Synonyms	260353-65-9 CTK1A0543 AKOS027403822 (-)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid DTXSID10431169 (+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid BDBM50094842 2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid AFBD SCHEMBL1088473 (+/-)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-amino-6-fluoro-, (1R,2S,5R,6R)- [ Show all ]
Inchi Key	GLDRBCJXSGSXEU-JKBXLQNXSA-N
Inchi ID	InChI=1S/C8H10FNO4/c9-8(6(13)14)3-1-2-7(10,4(3)8)5(11)12/h3-4H,1-2,10H2,(H,11,12)(H,13,14)/t3-,4-,7+,8-/m1/s1
PubChem CID	9815617
ChEMBL	CHEMBL333519
IUPHAR	N/A
BindingDB	50094842
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99229	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
99224	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
99230	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
99225	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
99227	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
99228	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
99226	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
99231	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
99223	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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