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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	15(R)-Prostaglandin E1
Molecular formula	C20H34O5
IUPAC name	7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight	354.487
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.2
Synonyms	7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid CHEMBL62570 UNII-V2N896SN9V 15R-PGE1 9-oxo-11R,15R-dihydroxy-13E-prostaenoic acid LMFA03010055 1213AH BDBM50101828 SR-01000946408 15-epi-PGE1 7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid HMS3648D07 V2N896SN9V 15R-Prostaglandin E1 AC1NR1FD Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11alpha,13E,15R)- 15(R)-PGE1 7-((1R,2R,3R)-3-Hydroxy-2-((1E,3R)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid SR-01000946408-1 15-Epiprostaglandin E1 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid J-013704 ZINC3830202 20897-91-0 Alprostadil impurity D [EP] SCHEMBL11786980 [ Show all ]
Inchi Key	GMVPRGQOIOIIMI-CHCORRSHSA-N
Inchi ID	InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17-,19-/m1/s1
PubChem CID	5283056
ChEMBL	CHEMBL62570
IUPHAR	N/A
BindingDB	50101828
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100247	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
100246	Prostaglandin D2 receptor	Q9R261	Ptgdr	Rattus norvegicus (Rat)	357
100248	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
100249	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
517848	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
555846	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
100243	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
517849	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
100244	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362
100245	Thromboxane A2 receptor	P30987	Tbxa2r	Mus musculus (Mouse)	341

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