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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	dimethylhistaprodifen
Molecular formula	C22H27N3
IUPAC name	2-[2-(3,3-diphenylpropyl)-1H-imidazol-5-yl]-N,N-dimethylethanamine
Molecular weight	333.479
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.5
Synonyms	D0PB6B 2-[2-[3,3-di(phenyl)propyl]-3H-imidazol-4-yl]-N,N-dimethylethanamine N,N-Dimethyl-2-(3,3-diphenylpropyl)-1H-imidazole-4-(ethanamine) PDSP1_001311 CHEMBL11553 GTPL1203 BDBM86170 PDSP2_001295 [ Show all ]
Inchi Key	GNBOIGBQIBQOIA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N3/c1-25(2)16-15-20-17-23-22(24-20)14-13-21(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17,21H,13-16H2,1-2H3,(H,23,24)
PubChem CID	10042467
ChEMBL	CHEMBL11553
IUPHAR	1203
BindingDB	86170
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100433	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
100435	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
100434	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
100436	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
100426	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
100427	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
100432	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
100431	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
100428	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445

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