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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Morphine-6-glucuronide
Molecular formula	C23H27NO9
IUPAC name	(2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular weight	461.467
Hydrogen bond acceptor	10
Hydrogen bond donor	5
XlogP	-2.9
Synonyms	(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-{[(1S,5R,13R,14S,17R)-10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0;{1,13}.0;{5,17}.0;{7,18}]octadeca-7(18),8,10,15-tetraen-14-yl]oxy}oxane-2-carboxylic acid BDBM50370478 Glucopyranosiduronic acid, 7,8-didehydro-4,5-alpha-epoxy-3-hydroxy-17-methylmorphinan-6-alpha-yl-, beta-D- MORPHINE 6-GLUCURONIDE(MINOR) SCHEMBL152647 20290-10-2 CHEBI:80581 Morphine 6-beta-D-glucopyranosiduronide Morphine-6-beta-D-glucuronide solution, 1.0 mg/mL in methanol: water (2:8), ampule of 1 mL, certified reference material D01UXW Morphine 6-beta-D-Glucuronide 1.0 mg/ml in Water morphine-glucuronide (2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-hydroxy-17-methylmorphinan-6-yl GNJCUHZOSOYIEC-GAROZEBRSA-N MORPHINE GLUCURONIDE UNII-64Y9KYM60R 28932-95-8 Morphine 6-beta-D-Glucuronide Morphine-6-beta-D-glucuronide solution, 100 mug/mL in methanol: water (1:1), ampule of 1 mL, certified reference material 64Y9KYM60R DTXSID40174158 Morphine 6-glucuronide PDSP2_000436 155755-06-9 C16578 LS-71638 Morphine glucuronide [INN] ZINC14089740 32205-91-7 CHEMBL1330 Morphine 6-beta-D-Glucuronide 0.1 mg/ml in Water [ Show all ]
Inchi Key	GNJCUHZOSOYIEC-GAROZEBRSA-N
Inchi ID	InChI=1S/C23H27NO9/c1-24-7-6-23-10-3-5-13(31-22-17(28)15(26)16(27)19(33-22)21(29)30)20(23)32-18-12(25)4-2-9(14(18)23)8-11(10)24/h2-5,10-11,13,15-17,19-20,22,25-28H,6-8H2,1H3,(H,29,30)/t10-,11+,13-,15-,16-,17+,19-,20-,22+,23-/m0/s1
PubChem CID	5360621
ChEMBL	CHEMBL1330
IUPHAR	N/A
BindingDB	50370478
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
524470	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
100603	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
100604	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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