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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CTEP
Molecular formula	C19H13ClF3N3O
IUPAC name	2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine
Molecular weight	391.778
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.6
Synonyms	2-?chloro-?4-?((2,?5-?dimethyl-?1-?(4-?(trifluoromethoxy)?phenyl)?-?1H-?imidazol-?4-?yl)?ethynyl)?pyridine AKOS027301517 CHEMBL3410223 FT-0749890 mGluR5 inhibitor W-5971 2340AH AS-17058 HMS3651N19 QC-11673 C19H13ClF3N3O DTXSID50469986 KB-76209 SCHEMBL608379 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine AM808005 compound 3 [PMID: 25565255] GTPL6408 MolPort-035-395-697 ZINC35996961 BCP06140 CTEP (RO4956371) HY-15445 RO 4956371 1-(3,5-bis(trifluoromethyl)phenyl)-3-(4-bromo-2-(1h-tetrazol-5-yl)phenyl)thiourea 871362-31-1 EX-A095 KS-000006G1 SW219465-1 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine AOB87758 CS-0974 GTPL6409 NCGC00386156-06 [3H]CTEP BDBM50071375 D0H2LI J-690373 s2861 [ Show all ]
Inchi Key	GOHCTCOGYKAJLZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H13ClF3N3O/c1-12-17(8-3-14-9-10-24-18(20)11-14)25-13(2)26(12)15-4-6-16(7-5-15)27-19(21,22)23/h4-7,9-11H,1-2H3
PubChem CID	11646823
ChEMBL	CHEMBL3410223
IUPHAR	6409, 6408
BindingDB	50071375
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101202	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
553754	Metabotropic glutamate receptor 5	Q3UVX5	Grm5	Mus musculus (Mouse)	1203
553755	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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