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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL246107
Molecular formula	C28H36N4O6
IUPAC name	2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-[4-(4-morpholin-4-ylbutyl)furan-2-yl]propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
Molecular weight	524.618
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	3.3
Synonyms	SCHEMBL12087259 (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-(4-morpholinobutyl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide BDBM50211461
Inchi Key	GOXKLDRNSZHYPN-HXUWFJFHSA-N
Inchi ID	InChI=1S/C28H36N4O6/c1-4-20(22-16-18(17-38-22)8-5-6-11-32-12-14-37-15-13-32)29-23-24(27(35)26(23)34)30-21-10-7-9-19(25(21)33)28(36)31(2)3/h7,9-10,16-17,20,29-30,33H,4-6,8,11-15H2,1-3H3/t20-/m1/s1
PubChem CID	10481927
ChEMBL	CHEMBL246107
IUPHAR	N/A
BindingDB	50211461
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101645	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
101644	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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