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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL372803
Molecular formula	C31H31Cl2N5O3
IUPAC name	2-[(3R)-3-acetamidopyrrolidin-1-yl]-N-[2-[4-(3-cyanophenyl)phenyl]ethyl]-N-[2-(3,5-dichloroanilino)-2-oxoethyl]acetamide
Molecular weight	592.521
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.8
Synonyms	BDBM50174818 2-((R)-3-acetylamino-pyrrolidin-1-yl)-N-[2-(3''-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-acetamide
Inchi Key	GPVBHNJUYAYUAV-MUUNZHRXSA-N
Inchi ID	InChI=1S/C31H31Cl2N5O3/c1-21(39)35-28-10-11-37(18-28)20-31(41)38(19-30(40)36-29-15-26(32)14-27(33)16-29)12-9-22-5-7-24(8-6-22)25-4-2-3-23(13-25)17-34/h2-8,13-16,28H,9-12,18-20H2,1H3,(H,35,39)(H,36,40)/t28-/m1/s1
PubChem CID	10188732
ChEMBL	CHEMBL372803
IUPHAR	N/A
BindingDB	50174818
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
102295	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
102294	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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