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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001180182
Molecular formula	C14H14N4S2
IUPAC name	4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine
Molecular weight	302.414
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.0
Synonyms	AB00101255-01 2',4'-dimethyl-{N}-(4-methylpyridin-2-yl)-4,5'-bi-1,3-thiazol-2-amine BDBM97133 SMR000476285 4-(2,4-dimethyl-5-thiazolyl)-N-(4-methyl-2-pyridinyl)-2-thiazolamine;hydrobromide cid_2877321 ZINC4116988 AC1MEEXP MolPort-000-690-688 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine CCG-120129 SR-01000477299 MCULE-3732896271 [4-(2,4-dimethylthiazol-5-yl)thiazol-2-yl]-(4-methyl-2-pyridyl)amine;hydrobromide AKOS001700994 N-(4-methyl-2-pyridinyl)-N-[2',4'-dimethyl-4,5'-bis(1,3-thiazole)-2-yl]amine 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine;hydrobromide CHEMBL1740522 SR-01000477299-1 [ Show all ]
Inchi Key	GSIAWGVMMLXTJT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14N4S2/c1-8-4-5-15-12(6-8)18-14-17-11(7-19-14)13-9(2)16-10(3)20-13/h4-7H,1-3H3,(H,15,17,18)
PubChem CID	2877322
ChEMBL	N/A
IUPHAR	N/A
BindingDB	97133
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
104132	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368

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