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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL378515
Molecular formula	C18H20ClN5O
IUPAC name	6-chloro-2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]imidazo[1,2-b]pyridazine
Molecular weight	357.842
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.7
Synonyms	BDBM50189840 6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Inchi Key	GSYFEKZSWFXBAB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20ClN5O/c1-25-16-5-3-2-4-15(16)23-10-8-22(9-11-23)12-14-13-24-18(20-14)7-6-17(19)21-24/h2-7,13H,8-12H2,1H3
PubChem CID	11581237
ChEMBL	CHEMBL378515
IUPHAR	N/A
BindingDB	50189840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
104572	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
104571	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
104570	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
104575	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
104573	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
104574	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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