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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-(1,1-dimethylpropyl)-5-[(5,7-dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)methyl]-2-methoxybenzenesulfonamide
Molecular formula	C20H23N3O5S
IUPAC name	5-[(5,7-dioxopyrrolo[3,4-b]pyridin-6-yl)methyl]-2-methoxy-N-(2-methylbutan-2-yl)benzenesulfonamide
Molecular weight	417.48
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.1
Synonyms	ZINC6998423 MCULE-9189703861 AB00827092-06 CHEMBL1456385 MLS001199843 AKOS001951434 SMR000563946 HMS2873A04 MolPort-007-771-509 [ Show all ]
Inchi Key	GWHRUBCOXYRRIM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N3O5S/c1-5-20(2,3)22-29(26,27)16-11-13(8-9-15(16)28-4)12-23-18(24)14-7-6-10-21-17(14)19(23)25/h6-11,22H,5,12H2,1-4H3
PubChem CID	20923165
ChEMBL	CHEMBL1456385
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
476121	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
106925	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
106927	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
106926	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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