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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(2S,1'S,2'S)-2-(carboxycyclopropyl)glycine
Molecular formula	C6H9NO4
IUPAC name	(1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
Molecular weight	159.141
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-3.4
Synonyms	117857-93-9 AKOS006275493 Cyclopropaneacetic acid, alpha-amino-2-carboxy-, (alphaS,1S,2S)- L-Ccg-I NCGC00024541-04 (1S,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanecarboxylic acid 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-CCG) C-237 GTPL1368 Lopac0_000374 SCHEMBL664330 L-2-(Carboxypropyl)glycine NCGC00024541-02 Tox21_500374 B6264 D0Z7CZ L-CCG-l NCGC00024541-05 (1S,2S)-2-[(1S)-1-amino-2-hydroxy-2-oxoethyl]cyclopropane-1-carboxylic acid 2S,1'S,2'S)-2-(Carboxycyclopropyl)Glycine CCG-204469 HMS3261K09 LP00374 SR-01000075799 (2S,3S,4S)-CCG AC1NSJQB CHEMBL280563 L-CCG-1 NCGC00024541-03 ZINC2568218 (1S,2S)-2-((S)-Amino(carboxy)methyl)cyclopropanecarboxylic acid 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid BDBM50034504 EU-0100374 L-CCGI NCGC00261059-01 (2S,1 inverted exclamation markaS,2 inverted exclamation markaS)-2-(Carboxycyclopropyl)glycine 3,4-Cyclopropylglutamate CCPG J-003677 MolPort-003-940-678 SR-01000075799-1 [ Show all ]
Inchi Key	GZOVEPYOCJWRFC-HZLVTQRSSA-N
Inchi ID	InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1
PubChem CID	5310956
ChEMBL	CHEMBL280563
IUPHAR	1368
BindingDB	50034504
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
109298	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
109308	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
109297	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
109303	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
109302	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
109305	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
109300	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
109301	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
109299	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
109304	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
109294	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
109309	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
109295	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
109307	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
109296	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908
109306	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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