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Ligand

Namedesipramine
Molecular formulaC18H22N2
IUPAC name3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
Molecular weight266.388
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP4.9
SynonymsNorimipramine
Desmethylimipramine
Desipramin
Demethylimipramine
Monodemethylimipramine
[ Show all ]
Inchi KeyHCYAFALTSJYZDH-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3
PubChem CID2995
ChEMBLCHEMBL72
IUPHARN/A
BindingDB35229
DrugBankDB01151

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 33
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
1117285-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1117515-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1117345-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1117275-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5559025-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1117395-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1117445-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1117335-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
5559035-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
111746Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
111748Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
111750Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
111738Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
111731Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
111747Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
111745Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
111732Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
460223Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
111730D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
111741D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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