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Ligand

Namezotepine
Molecular formulaC18H18ClNOS
IUPAC name2-(3-chlorobenzo[b][1]benzothiepin-5-yl)oxy-N,N-dimethylethanamine
Molecular weight331.858
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP4.8
Synonyms26615-21-4
Nipolept
Lodopin
Zoleptil
Zotepina
[ Show all ]
Inchi KeyHDOZVRUNCMBHFH-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
PubChem CID5736
ChEMBLCHEMBL285802
IUPHAR103
BindingDB35255
DrugBankDB09225

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 51
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
1121585-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1121745-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1121935-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
1121645-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1121845-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1121715-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5559055-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1121625-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1121945-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
1121575-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
1121905-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1121565-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
1121855-hydroxytryptamine receptor 7P32304Htr7Mus musculus (Mouse)448
5538135-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
112198Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
112199Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
112178Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
112170Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
112172Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
112183Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462

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