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Ligand

Name5-Methylurapidil
Molecular formulaC21H31N5O3
IUPAC name6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3,5-trimethylpyrimidine-2,4-dione
Molecular weight401.511
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP1.9
Synonyms5-Methyl-urapidil
Urapidil, 5-Methyl-
5 Methylurapidil
34661-85-3
UNII-1HLS600135
[ Show all ]
Inchi KeyHIHZDNKKIUQQSC-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3
PubChem CID5640
ChEMBLCHEMBL420060
IUPHAR489
BindingDB50033112
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 15
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1157365-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
115730Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
115732Alpha-1A adrenergic receptorQ9WU25ADRA1ACavia porcellus (Guinea pig)466
115733Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
115737Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
115739Alpha-1A adrenergic receptorO02824ADRA1AOryctolagus cuniculus (Rabbit)466
115728Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
115729Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
115731Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
115734Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
115735Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
115740Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
115738Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
555922D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
115727Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460

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