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Ligand

NameCHEMBL3804846
Molecular formulaC22H14F2N2O2
IUPAC name(4R,5R)-5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)pyridin-3-yl]-1,3-oxazolidin-2-one
Molecular weight376.363
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.9
SynonymsAKOS030629094
(4R,5R)-5-(2,5-difluorophenyl)-4-(5-(phenylethynyl)pyridin-3-yl)oxazolidin-2-one
SCHEMBL4541079
BDBM50169542
HIRXVQATYCZQHB-NHCUHLMSSA-N
[ Show all ]
Inchi KeyHIRXVQATYCZQHB-NHCUHLMSSA-N
Inchi IDInChI=1S/C22H14F2N2O2/c23-17-8-9-19(24)18(11-17)21-20(26-22(27)28-21)16-10-15(12-25-13-16)7-6-14-4-2-1-3-5-14/h1-5,8-13,20-21H,(H,26,27)/t20-,21-/m1/s1
PubChem CID57330204
ChEMBLCHEMBL3804846
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
524877Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
524878Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
524871Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
524875Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
524873Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
538837Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
524874Metabotropic glutamate receptor 6O15303GRM6Homo sapiens (Human)877
524876Metabotropic glutamate receptor 7Q14831GRM7Homo sapiens (Human)915
524872Metabotropic glutamate receptor 8O00222GRM8Homo sapiens (Human)908

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