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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL374867
Molecular formula	C32H39N5O5
IUPAC name	6-[4-[2-[[(2S)-3-[[3-(2-cyclobutylethyl)-2-oxo-1H-benzimidazol-4-yl]oxy]-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide
Molecular weight	573.694
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	3.9
Synonyms	BDBM50193804 (S)-6-(4-(2-(3-(3-(2-cyclobutylethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide
Inchi Key	HJPFFQXHOWOXMX-DEOSSOPVSA-N
Inchi ID	InChI=1S/C32H39N5O5/c1-32(2,17-22-9-12-25(13-10-22)42-28-14-11-23(18-34-28)30(33)39)35-19-24(38)20-41-27-8-4-7-26-29(27)37(31(40)36-26)16-15-21-5-3-6-21/h4,7-14,18,21,24,35,38H,3,5-6,15-17,19-20H2,1-2H3,(H2,33,39)(H,36,40)/t24-/m0/s1
PubChem CID	16126657
ChEMBL	CHEMBL374867
IUPHAR	N/A
BindingDB	50193804
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
116641	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
116640	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
116638	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
116639	Beta-3 adrenergic receptor	P26255	Adrb3	Rattus norvegicus (Rat)	400

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