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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Dau 6285
Molecular formula	C17H21N3O4
IUPAC name	(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 6-methoxy-2-oxo-3H-benzimidazole-1-carboxylate
Molecular weight	331.372
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.1
Synonyms	Dau-6285 BDBM50007863 PDSP1_000035 123258-98-0 D04GSA PDSP2_001663 6-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride GTPL246 CHEMBL1194556 PDSP1_001680 SCHEMBL2945410 AC1L2WHB L000897 (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 6-methoxy-2-oxo-3H-benzimidazole-1-carboxylate CHEMBL552854 PDSP2_000035 [ Show all ]
Inchi Key	HKBNGEJJECJLOW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-9-12(23-2)5-6-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21)
PubChem CID	129928
ChEMBL	N/A
IUPHAR	246
BindingDB	50007863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553860	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
553861	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
555929	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
555930	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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