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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000060129
Molecular formula	C19H20N2O5
IUPAC name	ethyl 5-[5-(2,4-dihydroxy-5-propylphenyl)-1H-pyrazol-4-yl]furan-2-carboxylate
Molecular weight	356.378
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.8
Synonyms	BDBM61793 HMS1768L06 ZINC13126196 cid_5428930 MLS002637231 AC1Q2USO ethyl 5-[3-(2,4-dihydroxy-5-propylphenyl)-1H-pyrazol-4-yl]furan-2-carboxylate SCHEMBL14396168 5-[(3Z)-3-(4-hydroxy-6-keto-3-propyl-cyclohexa-2,4-dien-1-ylidene)-3-pyrazolin-4-yl]furan-2-carboxylic acid ethyl ester HMS2488F16 AC1NTFTA ethyl 5-[(3Z)-3-(4-hydroxy-6-oxo-3-propylcyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazol-4-yl]furan-2-carboxylate Oprea1_317137 AKOS001036615 ethyl 5-[3-(4-hydroxy-6-oxo-3-propylcyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazol-4-yl]furan-2-carboxylate 5-[(3Z)-3-(4-hydroxy-6-oxo-3-propyl-1-cyclohexa-2,4-dienylidene)-1,2-dihydropyrazol-4-yl]-2-furancarboxylic acid ethyl ester CHEMBL1541596 MLS000055604 AC1OA5YE ethyl 5-[(3Z)-3-(4-oxidanyl-6-oxidanylidene-3-propyl-cyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazol-4-yl]furan-2-carboxylate Oprea1_690537 [ Show all ]
Inchi Key	HKTSJOVFAVYHKL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20N2O5/c1-3-5-11-8-12(15(23)9-14(11)22)18-13(10-20-21-18)16-6-7-17(26-16)19(24)25-4-2/h6-10,22-23H,3-5H2,1-2H3,(H,20,21)
PubChem CID	984148
ChEMBL	CHEMBL1541596
IUPHAR	N/A
BindingDB	61793
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
560937	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
560934	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
560935	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
560936	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
560938	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
560939	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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