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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL175523
Molecular formula	C29H33N5O6S2
IUPAC name	4-tert-butyl-N-[5-(3,4-dimethoxyphenyl)-6-[2-(5-methylsulfanylpyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]benzenesulfonamide
Molecular weight	611.732
Hydrogen bond acceptor	12
Hydrogen bond donor	1
XlogP	5.4
Synonyms	BDBM50105047 HLTLKXRFUHPDRK-UHFFFAOYSA-N CHEMBL1181531 N-[5-(3,4-Dimethoxyphenyl)-6-[2-[5-(methylthio)-2-pyrimidinyloxy]ethoxy]-4-pyrimidinyl]-4-tert-butylbenzenesulfonamide Acetic acid ethyl ester4-tert-Butyl-N-{5-(3,4-dimethoxy-phenyl)-6-[2-(5-methylsulfanyl-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide 4-tert-butyl-N-{5-(3,4-dimethoxyphenyl)-6-[2-(5-methylthiopyrimidin-2-yloxy)ethoxy]-pyrimidin-4-yl}benzenesulfonamide SCHEMBL8656702 [ Show all ]
Inchi Key	HLTLKXRFUHPDRK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H33N5O6S2/c1-29(2,3)20-8-10-22(11-9-20)42(35,36)34-26-25(19-7-12-23(37-4)24(15-19)38-5)27(33-18-32-26)39-13-14-40-28-30-16-21(41-6)17-31-28/h7-12,15-18H,13-14H2,1-6H3,(H,32,33,34)
PubChem CID	11767252
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50105047
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
118219	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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