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Ligand

NameA-119637
Molecular formulaC25H26N4O3S
IUPAC name3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione
Molecular weight462.568
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.9
SynonymsCHEMBL268758
D0Q7ZR
A119637
GTPL490
SCHEMBL7837611
[ Show all ]
Inchi KeyHLVQBOYEHQRWHG-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)
PubChem CID9890547
ChEMBLCHEMBL268758
IUPHAR490
BindingDB50099322
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 12
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
118308Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
118311Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
118312Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
118305Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
118307Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
118309Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
118314Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
118306Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
118315Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
118310Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
118316D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
118313D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444

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