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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922024
Molecular formula	C28H35FN6O2
IUPAC name	4-N-(3-fluoro-4-methoxyphenyl)-2-N-(4-methoxyphenyl)-6-(4-piperidin-1-ylpiperidin-1-yl)pyrimidine-2,4-diamine
Molecular weight	506.626
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.9
Synonyms	BDBM50358672 SCHEMBL10144327
Inchi Key	HNGUGPWVISDANL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H35FN6O2/c1-36-23-9-6-20(7-10-23)31-28-32-26(30-21-8-11-25(37-2)24(29)18-21)19-27(33-28)35-16-12-22(13-17-35)34-14-4-3-5-15-34/h6-11,18-19,22H,3-5,12-17H2,1-2H3,(H2,30,31,32,33)
PubChem CID	57401227
ChEMBL	CHEMBL1922024
IUPHAR	N/A
BindingDB	50358672
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119345	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
119346	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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