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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	methapyrilene
Molecular formula	C14H19N3S
IUPAC name	N,N-dimethyl-N'-pyridin-2-yl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine
Molecular weight	261.387
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.6
Synonyms	Histase Tenalin KBio3_002968 ZINC2510048 Lullamin Methacon (Salt/Mix) Methapyriline N-(alpha-Pyridyl)-N-(alpha-thenyl)-N',N'-dimethylethylenediamine 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine NCI-C09018 AB00053658_13 Prestwick3_000342 BSPBio_000403 RCRA waste number U155 SPBio_002171 Spectrum3_001902 IDI1_000928 Thenylene L001018 Metapirilene Methapyrilene Solution, 2000 microg/mL in Dichloromethane N,N-Dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamine NCGC00015704-03 91-80-5 NSC_4098 BDBM81469 Pyridine, 2-((2-(dimethylamino)ethyl)-2-thenylamino)- CAS-135-23-9 SBI-0050827.P003 DivK1c_000928 Spectrum_001573 KBio2_004621 Thionylan LS-1929 Metapirileno [INN-Spanish] Methapyrilenum N,N-dimethyl-N'-pyridin-2-yl-N'-[(thiophen-2-yl)methyl]ethane-1,2-diamine 2-((2-(Dimethylamino)ethyl)-2-thenylamino)pyridine NCGC00015704-06 AB00053658 Prestwick1_000342 BRD-K47323024-003-15-2 Pyrinistol CCRIS 5429 Sleepwell Histadryl HNJJXZKZRAWDPF-UHFFFAOYSA-N Tenalin base KBioGR_000691 Lullamin (Salt/Mix) methypyrilene NCGC00015704-01 5-22-08-00401 (Beilstein Handbook Reference) NCI-C55550 AC1L1HEP Pyrahistine BSPBio_003464 Rest-on CHEMBL1411979 SPBio_002324 Spectrum4_000176 KBio1_000928 Thenylene base Lopac-M-9125 Metapirilene [DCIT] Methapyrilene [INN:BAN] N,N-dimethyl-N'-pyridin-2-yl-N'-(2-thienylmethyl)ethane-1,2-diamine NCGC00015704-04 A 3322 Paradormalene BPBio1_000445 Pyridine, 2-[[2-(dimethylamino)ethyl]-2-thenylamino]- CAS_91-80-5 SCHEMBL19209 DTXSID2023278 Histadyl (Salt/Mix) Tem-Histine (Salt/Mix) KBio2_007189 UNII-A01LX40298 Lulamin Metapyrilene Methapyrilenum [INN-Latin] N-(.alpha.-Pyridyl)-N-(.alpha.-thenyl)-N',N'-dimethylethylenediamine 2-[(2-dimethylaminoethyl)-2-thenylamino]pyridine NCGC00162277-01 AB00053658_12 Prestwick2_000342 BRN 0220729 RCRA waste no. U155 CHEBI:6820 Somnicaps (Salt/Mix) HSDB 4163 Teralin (Salt/Mix) KBioSS_002053 MCULE-7834983827 METHAPYRILENE (SEE ALSO METHAPYRILENE HYDROCHLORIDE 135-23-9) N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine NCGC00015704-02 NINDS_000928 AH-42 Pyrathyn C11114 Restryl CTK6I0815 Spectrum2_001986 Spectrum5_001017 KBio2_002053 Thenylpyramine Lopac0_000851 Metapirileno Methapyrilene, (base) N,N-dimethyl-N'-pyridin-2-yl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine 1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)- NCGC00015704-05 A01LX40298 Prestwick0_000342 BRD-K47323024-003-05-3 Pyrinistab CCG-204934 Semikon EINECS 202-099-8 [ Show all ]
Inchi Key	HNJJXZKZRAWDPF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H19N3S/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14/h3-8,11H,9-10,12H2,1-2H3
PubChem CID	4098
ChEMBL	CHEMBL1411979
IUPHAR	N/A
BindingDB	81469
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119423	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
119425	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
119421	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
119419	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
119417	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
119416	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
119418	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
119422	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
119426	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
119427	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
119424	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
119420	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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