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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL313714
Molecular formula	C26H31FN6O
IUPAC name	(2R)-2-(4-fluorophenyl)-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethanol
Molecular weight	462.573
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.9
Synonyms	(2R)-2-(4-fluorophenyl)-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethanol GTPL16 L-772405 (R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol L 772405 BDBM50060429 SCHEMBL4339517 D01HRV L-772,405 [ Show all ]
Inchi Key	HNKDAQNYMJNLCC-SANMLTNESA-N
Inchi ID	InChI=1S/C26H31FN6O/c27-21-5-3-19(4-6-21)26(16-34)31-22-9-12-32(13-10-22)11-1-2-20-15-28-25-8-7-23(14-24(20)25)33-17-29-30-18-33/h3-8,14-15,17-18,22,26,28,31,34H,1-2,9-13,16H2/t26-/m0/s1
PubChem CID	9847194
ChEMBL	CHEMBL313714
IUPHAR	16
BindingDB	50060429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
119444	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
119443	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
119439	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
119445	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
119442	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
119441	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
119440	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
119446	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
119447	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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