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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3819427
Molecular formula	C20H22N2O2
IUPAC name	4-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butanoyl]benzamide
Molecular weight	322.408
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.3
Synonyms	BDBM50182739 SCHEMBL20358377
Inchi Key	HNPAUMYBQXZAJH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22N2O2/c21-20(24)17-9-7-16(8-10-17)19(23)6-3-12-22-13-11-15-4-1-2-5-18(15)14-22/h1-2,4-5,7-10H,3,6,11-14H2,(H2,21,24)
PubChem CID	127051844
ChEMBL	CHEMBL3819427
IUPHAR	N/A
BindingDB	50182739
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
524994	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
524992	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
524997	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
524993	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
525000	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
524996	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
524998	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
524995	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
524999	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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