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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3608740
Molecular formula	C16H16N6OS
IUPAC name	[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-phenylmethanone
Molecular weight	340.405
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.5
Synonyms	BDBM50112179 SCHEMBL16143073
Inchi Key	HQFWWFCJWZXHFM-SNVBAGLBSA-N
Inchi ID	InChI=1S/C16H16N6OS/c1-10-13-18-19-14(15-17-11(2)20-24-15)22(13)9-8-21(10)16(23)12-6-4-3-5-7-12/h3-7,10H,8-9H2,1-2H3/t10-/m1/s1
PubChem CID	86275207
ChEMBL	CHEMBL3608740
IUPHAR	N/A
BindingDB	50112179
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
477860	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
477861	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
561079	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
561078	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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