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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-Methoxyidazoxan
Molecular formula	C12H14N2O3
IUPAC name	2-(3-methoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
Molecular weight	234.255
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.5
Synonyms	1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro- (9CI) 2-ethoxy-idazoxan AC1L33BW CHEMBL10332 KBioSS_002301 PDSP1_000805 Spectrum_001808 (-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole 2-(2-methoxy-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole 2-[2-(2-methoxy-1,4-benzodioxanyl)]imidazoline BDBM50019492 GTPL526 LS-78462 RX 821001 102575-24-6 2-(2-methoxy-3H-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole CHEBI:73287 KBio2_004867 NCGC00015903-04 RX821002 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole alpha-methoxyidazoxan D08KLH L001007 PDSP2_000792 [3H]2-methoxyidazoxan 2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole 476M359 BRD-A65597028-003-02-4 GTPL528 MCULE-7578829705 RX 821002 1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro- 2-(3-methoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole KBio2_007435 NCGC00025112-02 SCHEMBL2494824 [3H]RX821002 (+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole 2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline 2-[2-(2-Methoxy-1,4-benzodioanyl)]-imidazoline BCP14552 D0ZB3X Lopac0_001053 PubChem2676 1,4-Benzodioxin, 1H-imidazole deriv. 2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole CCG-205130 KBio2_002299 NCGC00015903-03 RX-821002 [ Show all ]
Inchi Key	HQGWKNGAKBPTBX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)
PubChem CID	108094
ChEMBL	CHEMBL10332
IUPHAR	526, 528
BindingDB	50019492
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
121362	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
121363	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
121365	Alpha-2A adrenergic receptor	Q01338	Adra2a	Mus musculus (Mouse)	450
121366	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
121360	Alpha-2B adrenergic receptor	O77830	ADRA2B	Oryctolagus cuniculus (Rabbit)	394
121361	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
121364	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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