Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	128143-88-4
Molecular formula	C15H11N3O
IUPAC name	2,6-dipyridin-2-yl-1H-pyridin-4-one
Molecular weight	249.273
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.3
Synonyms	J-005568 SC-70393 2,6-bis-pyridyl-4-(1H)-pyridone ACMC-209bep CTK0H4325 KS-00000USR ZB013138 1'H-[2,2';6',2 '']terpyridine-4'-one 2,6-Bis(2-pyridyl)-4(1H)-pyridone 4-Terpyridone AKOS015912996 AX8067954 I14-41476 MolPort-020-169-847 [2,2':6',2''-Terpyridin]-4'-ol 1'H-[2,2';6',2'']terpyridine-4'-one 2,6-bis(pyridin-2-yl)-4(1h)-pyridone AC-27853 CHEMBL2205804 J-400598 SCHEMBL1988750 2,2':6',2''-Terpyridin-4'-ol 2,6-dipyridin-2-yl-1H-pyridin-4-one ACMC-20m41v EOS227 KS-00001KN4 ZINC403259 1'H-[2,2';6',2'']terpyridin-4'-on 2,6-Bis(2-pyridyl)-4(1H)-pyridone, 98% AKOS015914629 BDBM50401356 I14-48284 OC1=CC(=NC(=C1)C1=CC=CC=N1)C1=NC=CC=C1 [2,2,6,2-terpyridin]-4(1H)-one 101003-65-0 2,6-Bis(pyridine-2-yl)pyridine-4(1H)-one AC1LDIYW CTK0H0167 KB-280983 Z2460 1'H-[2,2',6',2'']Terpyridin-4'-one 2,6-?Bis(2-?pyridyl)?-?4(1H)-pyridone 4'-HYDROXY-2,2':6',2''-TERPYRIDINE AJ-22002 HRORSVNZQWCZTD-UHFFFAOYSA-N MolPort-003-934-494 [2,2':6',2''-Terpyridin]-4'(1'H)-one 1'H-[2,2';6',2'']terpyridin-4'-one 2,6-Bis(2-pyridyl)-4(1H)-pyridone,98% 6-(pyridin-2-yl)-[2,2'-bipyridine]-4-ol ANW-19055 [ Show all ]
Inchi Key	HRORSVNZQWCZTD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H11N3O/c19-11-9-14(12-5-1-3-7-16-12)18-15(10-11)13-6-2-4-8-17-13/h1-10H,(H,18,19)
PubChem CID	619353
ChEMBL	CHEMBL2205804
IUPHAR	N/A
BindingDB	50401356
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
122258	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
122260	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
122259	C-C chemokine receptor type 8	P51685	CCR8	Homo sapiens (Human)	355

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218