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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL542436
Molecular formula	C17H25NO2
IUPAC name	(1R,3S)-1-(aminomethyl)-3-cyclohexyl-6-methyl-3,4-dihydro-1H-isochromen-5-ol
Molecular weight	275.392
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.1
Synonyms	CHEMBL1191350 (1R)-1alpha-(Aminomethyl)-3,4-dihydro-3alpha-cyclohexyl-6-methyl-1H-2-benzopyran-5-ol BDBM50008825 SCHEMBL9802432 1-Aminomethyl-3-cyclohexyl-6-methyl-isochroman-5-ol; hydrobromide
Inchi Key	HSJYTPFWWPUYDT-HOTGVXAUSA-N
Inchi ID	InChI=1S/C17H25NO2/c1-11-7-8-13-14(17(11)19)9-15(20-16(13)10-18)12-5-3-2-4-6-12/h7-8,12,15-16,19H,2-6,9-10,18H2,1H3/t15-,16-/m0/s1
PubChem CID	15711850
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50008825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
122874	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
122873	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
122872	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415
561127	D(1) dopamine receptor	P35406		Carassius auratus (Goldfish)	363
122875	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
122871	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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