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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL52625
Molecular formula	C21H20FN5
IUPAC name	7-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	361.424
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.0
Synonyms	6-[4-(4-Fluorobenzyl)-1-piperazinyl]pyrido[3,2-e]pyrrolo[1,2-a]pyrazine BDBM50408164 SCHEMBL8569998
Inchi Key	HSLUKGWVBNRWNC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20FN5/c22-17-7-5-16(6-8-17)15-25-11-13-26(14-12-25)21-19-4-2-10-27(19)20-18(24-21)3-1-9-23-20/h1-10H,11-15H2
PubChem CID	10666301
ChEMBL	CHEMBL52625
IUPHAR	N/A
BindingDB	50408164
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
122919	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
122920	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
122921	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
122918	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
122922	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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