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Ligand

NameGalanin rat
Molecular formulaC92H135N27O26
IUPAC name3-[[2-[2-[[2-[[1-[2-[[2-[[2-[[2-[[2-[2-[[2-[[4-amino-2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]propanoylamino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoylamino]-3-methylpentanoyl]amino]-4-[[4-amino-1-[[1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid
Molecular weight2035.26
Hydrogen bond acceptor29
Hydrogen bond donor28
XlogP-6.9
SynonymsGalanin (1-19), rat
BDBM85200
Inchi KeyHTINXISERLHZAZ-UHFFFAOYSA-N
Inchi IDInChI=1S/C92H135N27O26/c1-12-46(8)75(91(144)115-66(33-74(128)129)87(140)112-64(31-69(94)123)85(138)108-57(77(96)130)29-52-36-97-41-102-52)117-79(132)48(10)105-81(134)63(30-53-37-98-42-103-53)113-90(143)68-18-15-23-119(68)73(127)39-101-80(133)58(24-43(2)3)109-82(135)59(25-44(4)5)110-84(137)61(27-50-19-21-54(122)22-20-50)107-72(126)38-100-78(131)47(9)104-89(142)67(40-120)116-86(139)65(32-70(95)124)111-83(136)60(26-45(6)7)114-92(145)76(49(11)121)118-88(141)62(106-71(125)34-93)28-51-35-99-56-17-14-13-16-55(51)56/h13-14,16-17,19-22,35-37,41-49,57-68,75-76,99,120-122H,12,15,18,23-34,38-40,93H2,1-11H3,(H2,94,123)(H2,95,124)(H2,96,130)(H,97,102)(H,98,103)(H,100,131)(H,101,133)(H,104,142)(H,105,134)(H,106,125)(H,107,126)(H,108,138)(H,109,135)(H,110,137)(H,111,136)(H,112,140)(H,113,143)(H,114,145)(H,115,144)(H,116,139)(H,117,132)(H,118,141)(H,128,129)
PubChem CID57340017
ChEMBLN/A
IUPHARN/A
BindingDB85200
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
123502Galanin receptor type 1P47211GALR1Homo sapiens (Human)349
123505Galanin receptor type 1Q62805Galr1Rattus norvegicus (Rat)346
123503Galanin receptor type 2O43603GALR2Homo sapiens (Human)387
123507Galanin receptor type 2O08726Galr2Rattus norvegicus (Rat)372
123504Galanin receptor type 3O60755GALR3Homo sapiens (Human)368
123506Galanin receptor type 3O88626Galr3Rattus norvegicus (Rat)370

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