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Ligand

NameJNJ-7777120
Molecular formulaC14H16ClN3O
IUPAC name(5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Molecular weight277.752
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP2.3
Synonyms459168-41-3
JNJ7777120
JNJ 7777120
UNII-4H1AU2V37X
HUQJRYMLJBBEDO-UHFFFAOYSA-N
[ Show all ]
Inchi KeyHUQJRYMLJBBEDO-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3
PubChem CID4908365
ChEMBLCHEMBL129198
IUPHAR1278, 1279
BindingDB22566
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
124520Histamine H1 receptorP70174Hrh1Mus musculus (Mouse)488
124521Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488
124524Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
124519Histamine H2 receptorP47747HRH2Cavia porcellus (Guinea pig)359
124522Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
124518Histamine H3 receptorQ9QYN8Hrh3Rattus norvegicus (Rat)445
124523Histamine H3 receptorQ9Y5N1HRH3Homo sapiens (Human)445
124515Histamine H4 receptorQ9H3N8HRH4Homo sapiens (Human)390
124516Histamine H4 receptorQ91ZY1Hrh4Rattus norvegicus (Rat)391
124517Histamine H4 receptorQ91ZY2Hrh4Mus musculus (Mouse)391

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