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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2207641
Molecular formula	C34H40N4O2
IUPAC name	1-(2-methoxyphenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Molecular weight	536.72
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.7
Synonyms	BDBM50401944
Inchi Key	HVGNYVOUQOKFLU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H40N4O2/c1-39-33-14-8-6-12-31(33)37-20-16-35(17-21-37)25-27-24-28(30-11-5-3-4-10-29(27)30)26-36-18-22-38(23-19-36)32-13-7-9-15-34(32)40-2/h3-15,24H,16-23,25-26H2,1-2H3
PubChem CID	71454295
ChEMBL	CHEMBL2207641
IUPHAR	N/A
BindingDB	50401944
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
124934	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
124933	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
124930	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
124929	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
525162	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
124932	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
124936	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
124935	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
124931	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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