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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	trihexyphenidyl
Molecular formula	C20H31NO
IUPAC name	1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
Molecular weight	301.474
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.5
Synonyms	5-20-02-00231 (Beilstein Handbook Reference) Spectrum3_001375 Apo-Trihex Trihexifenidilo [INN-Spanish] Benzhexolum Trihexyphenidyl [INN:BAN] CAS_58947-95-8 HWHLPVGTWGOCJO-UHFFFAOYSA-N KBioGR_000837 MRF-0000523 (RS)-1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol NSC-12268 1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol Prestwick2_000701 SCHEMBL34645 AB00053559 Spectrum_000632 Artane (TN) Trihexylphenidyl BRD-A48180038-003-15-1 Trihexyphenidylum DTXSID4023705 KBio1_000372 Lopac0_001125 NCGC00016003-06 .alpha.-Cyclohexyl-.alpha.-phenyl-1-piperidinepropanol Oprea1_853391 119618-EP2269989A1 SPBio_002802 AKOS015914081 Trihexane BDBM81462 BSPBio_002930 D09GFL H2264 KBio2_006248 MFCD00599600 (R)-1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol NINDS_000372 1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol Prestwick0_000701 144T116 52-49-3 (hydrochloride) Spectrum4_000369 Apo-trihex (TN) Trihexy BPBio1_000971 Trihexyphenidyle CCG-205200 DB00376 I14-44543 KBioSS_001112 NCGC00016003-03 (s)-trihexyphenidyl NSC12268 1-Piperidinepropanol, .alpha.-cyclohexyl-.alpha.-phenyl- Prestwick3_000701 Sedrena (free base) AB00053559_13 STL300356 Artane Sequels Trihexylphenidyle BRN 0088959 Trihexyphenidylum [INN-Latin] CHEMBL1490 EINECS 205-614-4 KBio2_001112 LS-116010 NCGC00016003-07 1-Cyclohexyl-1-phenyl-3-(1-piperidinyl)-1-propanol # Parkinane retard 119618-EP2298731A1 40520-25-0 Spectrum2_000829 AN-23267 Trihexifenidilo Benzhexol Trihexyphenidyl (INN) C07171 D0F5KZ HSDB 3196 KBio3_002150 MolPort-001-783-510 (R)-trihexyphenidyl NSC 12268 1-Cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol (HCl) Prestwick1_000701 Spectrum5_001465 Artane Trihexylphenedyl BRD-A48180038-003-05-2 Trihexyphenidyle [INN-French] CHEBI:9720 DivK1c_000372 IDI1_000372 L000821 NCGC00016003-04 NSC_5572 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl- SBI-0051093.P003 SPBio_000757 AC1L1KNB SWR-0342SA BBL024959 Trihexylphenizyl BSPBio_000881 Triphenidyl D08638 GTPL7315 KBio2_003680 MCULE-6065307656 (?)-Benzhexol NCGC00089797-02 1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol PMS Trihexyphenidyl 144-11-6 [ Show all ]
Inchi Key	HWHLPVGTWGOCJO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H31NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2
PubChem CID	5572
ChEMBL	CHEMBL1490
IUPHAR	N/A
BindingDB	81462
DrugBank	DB00376
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555976	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
125562	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
125563	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
125557	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
125558	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
125560	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
125564	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
125561	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
125565	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490
125559	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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