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Ligand

NameSB-269970
Molecular formulaC18H28N2O3S
IUPAC name3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol
Molecular weight352.493
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP2.9
Synonyms201038-74-6
SB 269970
(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol
CHEMBL282199
SB-269970-A
[ Show all ]
Inchi KeyHWKROQUZSKPIKQ-MRXNPFEDSA-N
Inchi IDInChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
PubChem CID6604889
ChEMBLCHEMBL282199
IUPHAR3247, 3233
BindingDB50098551
DrugBankDB13988

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 19
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1256495-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1256615-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1256605-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1256635-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1256575-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1256595-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
1256665-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1256675-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1256545-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1256565-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1256555-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
1256625-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
1256585-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1256505-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
1256515-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
1256525-hydroxytryptamine receptor 7P50407HTR7Cavia porcellus (Guinea pig)446
125664Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
125665D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
125653D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400

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