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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL389037
Molecular formula	C24H30N6O4
IUPAC name	(2S)-N-[(2S)-3-(1-benzylimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-6-oxopiperidine-2-carboxamide
Molecular weight	466.542
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.1
Synonyms	(2S)-1-{(2S)-3-(1-benzyl-1H-4-imidazolyl)-2-[(2S)-6-oxohexahydro-2-pyridinylcarboxamido]azolane-propanoyl}azolane-2-carboxamide BDBM50196458
Inchi Key	ICNQGPKTIHCJTK-UFYCRDLUSA-N
Inchi ID	InChI=1S/C24H30N6O4/c25-22(32)20-9-5-11-30(20)24(34)19(28-23(33)18-8-4-10-21(31)27-18)12-17-14-29(15-26-17)13-16-6-2-1-3-7-16/h1-3,6-7,14-15,18-20H,4-5,8-13H2,(H2,25,32)(H,27,31)(H,28,33)/t18-,19-,20-/m0/s1
PubChem CID	44422169
ChEMBL	CHEMBL389037
IUPHAR	N/A
BindingDB	50196458
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
129945	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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