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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1096182
Molecular formula	C27H23Cl3N4O2
IUPAC name	N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide
Molecular weight	541.857
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	6.9
Synonyms	BDBM50316513 N-((4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl)-5-methyl-1H-pyrazole-3-carboxamide ZINC49793637 KB-65309 CB1 inverse agonists (obesity), Merck N-[(4R)-6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide D0V0YM MK-5596 SCHEMBL1404590 IDUFEEHNNASCMH-HSZRJFAPSA-N [ Show all ]
Inchi Key	IDUFEEHNNASCMH-HSZRJFAPSA-N
Inchi ID	InChI=1S/C27H23Cl3N4O2/c1-14-10-22(34-33-14)25(35)31-23-13-27(2,3)36-26-20(23)12-19(15-4-6-16(28)7-5-15)24(32-26)18-9-8-17(29)11-21(18)30/h4-12,23H,13H2,1-3H3,(H,31,35)(H,33,34)/t23-/m1/s1
PubChem CID	24871527
ChEMBL	CHEMBL1096182
IUPHAR	N/A
BindingDB	50316513
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
130822	Cannabinoid receptor 1	P20272	Cnr1	Rattus norvegicus (Rat)	473
130824	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
130823	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
130825	Cannabinoid receptor 2	Q9QZN9	Cnr2	Rattus norvegicus (Rat)	360

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