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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL538489
Molecular formula	C14H16N2O6
IUPAC name	(2R,4R)-4-amino-1-[carboxy(phenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight	308.29
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	-4.7
Synonyms	(2R,4R)-4-amino-1-[carboxy(phenyl)methyl]pyrrolidine-2,4-dicarboxylic acid dihydrochloride CHEMBL1189303 BDBM50102121
Inchi Key	IFKSHDLSGHIKDQ-KWBIFUEGSA-N
Inchi ID	InChI=1S/C14H16N2O6/c15-14(13(21)22)6-9(11(17)18)16(7-14)10(12(19)20)8-4-2-1-3-5-8/h1-5,9-10H,6-7,15H2,(H,17,18)(H,19,20)(H,21,22)/t9-,10?,14-/m1/s1
PubChem CID	10091203
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50102121
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
460432	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
131965	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
561396	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871

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