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Ligand

NameGUANFACINE
Molecular formulaC9H9Cl2N3O
IUPAC nameN-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
Molecular weight246.091
Hydrogen bond acceptor1
Hydrogen bond donor2
XlogP2.0
Synonyms29110-47-2
Guanfacinum [INN-Latin]
Guanfacina [INN-Spanish]
Guanfacinum
Guanfacina
[ Show all ]
Inchi KeyINJOMKTZOLKMBF-UHFFFAOYSA-N
Inchi IDInChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)
PubChem CID3519
ChEMBLCHEMBL862
IUPHAR522
BindingDB81984
DrugBankDB01018

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1373255-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1373275-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1373195-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
447098Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
137318Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
137322Alpha-2A adrenergic receptorQ01338Adra2aMus musculus (Mouse)450
137321Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
137317Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
137326Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
137323D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
137324Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460

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