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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1098228
Molecular formula	C24H18N2O
IUPAC name	5-(2-methylquinolin-7-yl)-2-phenylmethoxybenzonitrile
Molecular weight	350.421
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.4
Synonyms	BDBM50317846 D01MAN 2-Benzoxy-5-(2-methylquinolin-7-yl)benzonitrile
Inchi Key	INOCIGKWKFGOCI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H18N2O/c1-17-7-8-19-9-10-21(14-23(19)26-17)20-11-12-24(22(13-20)15-25)27-16-18-5-3-2-4-6-18/h2-14H,16H2,1H3
PubChem CID	46888005
ChEMBL	CHEMBL1098228
IUPHAR	N/A
BindingDB	50317846
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
137462	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
137459	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
137461	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
137458	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
137463	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
137460	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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