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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ONO 8130
Molecular formula	C25H28N2O5S2
IUPAC name	4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoic acid
Molecular weight	500.628
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.6
Synonyms	MolPort-039-052-220 AKOS025293498 SCHEMBL212551 4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid BDBM190564 US9181187, Compound B CHEMBL3939289 ONO-8130 459841-96-4 Benzoic acid, 4-(((2,3-dihydro-6-((2-methylpropyl)((4-methyl-2-thiazolyl)sulfonyl)amino)-1H-inden-5-yl)oxy)methyl)- ZINC33973857 [ Show all ]
Inchi Key	IOXMDBQCUCDLAF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28N2O5S2/c1-16(2)13-27(34(30,31)25-26-17(3)15-33-25)22-11-20-5-4-6-21(20)12-23(22)32-14-18-7-9-19(10-8-18)24(28)29/h7-12,15-16H,4-6,13-14H2,1-3H3,(H,28,29)
PubChem CID	9827317
ChEMBL	CHEMBL3939289
IUPHAR	N/A
BindingDB	190564
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
518046	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405

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