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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3403619
Molecular formula	C26H27F3N2O3
IUPAC name	2-[6-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]acetic acid
Molecular weight	472.508
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.1
Synonyms	SCHEMBL946655 BDBM50063864 D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylam SC-92768
Inchi Key	ISBCPWVJRHMKFI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
PubChem CID	49839234
ChEMBL	CHEMBL3403619
IUPHAR	N/A
BindingDB	50063864
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
447239	Sphingosine 1-phosphate receptor 1	P48303	S1pr1	Rattus norvegicus (Rat)	383
447240	Sphingosine 1-phosphate receptor 1	O08530	S1pr1	Mus musculus (Mouse)	382
447243	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
447241	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
447245	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
447242	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
447244	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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