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Ligand

NameTyr-Pro-D-(NMe)Phe-D-Pro-NH2
Molecular formulaC29H37N5O5
IUPAC name1-[2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2R)-1-[(2R)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-N-methylpyrrolidine-2-carboxamide
Molecular weight535.645
Hydrogen bond acceptor6
Hydrogen bond donor3
XlogP1.5
SynonymsD04IHL
CHEMBL163808
BDBM50044897
Inchi KeyJAKBYSTWCHUQOK-RULIFZQXSA-N
Inchi IDInChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22?,23-,24?,25-/m1/s1
PubChem CID44375783
ChEMBLN/A
IUPHARN/A
BindingDB50044897
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
145964Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
460549Delta-type opioid receptorP79291OPRD1Sus scrofa (Pig)228
145963Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
145966Kappa-type opioid receptorP41144OPRK1Cavia porcellus (Guinea pig)380
145965Mu-type opioid receptorP97266OPRM1Cavia porcellus (Guinea pig)98
556033Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400

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