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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tyr-Pro-D-(NMe)Phe-D-Pro-NH2
Molecular formula	C29H37N5O5
IUPAC name	1-[2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2R)-1-[(2R)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-N-methylpyrrolidine-2-carboxamide
Molecular weight	535.645
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.5
Synonyms	CHEMBL163808 D04IHL BDBM50044897
Inchi Key	JAKBYSTWCHUQOK-RULIFZQXSA-N
Inchi ID	InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22?,23-,24?,25-/m1/s1
PubChem CID	44375783
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50044897
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
145964	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
460549	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
145963	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
145966	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
145965	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
556033	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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