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Ligand

NameRS 67333
Molecular formulaC19H29ClN2O2
IUPAC name1-(4-amino-5-chloro-2-methoxyphenyl)-3-(1-butylpiperidin-4-yl)propan-1-one
Molecular weight352.903
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.8
SynonymsRS-67333
160845-95-4
1-(4-Amino-5-chloro-2-methoxyphenyl)-3-(1-butyl-4-piperidinyl)-1-propanone
1-(4-amino-5-chloro-2-methoxyphenyl)-3-(1-butylpiperidin-4-yl)propan-1-one
Tocris-0989
[ Show all ]
Inchi KeyJBHLYIVFFLNISJ-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H29ClN2O2/c1-3-4-9-22-10-7-14(8-11-22)5-6-18(23)15-12-16(20)17(21)13-19(15)24-2/h12-14H,3-11,21H2,1-2H3
PubChem CID183782
ChEMBLCHEMBL85251
IUPHAR237
BindingDB84950
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 15
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5560355-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1466845-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1466785-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
1466825-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
1466835-hydroxytryptamine receptor 4Q62758Htr4Rattus norvegicus (Rat)406
146679Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
146681Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
146687Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
146677Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
146685Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
460556Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
460555D(1A) dopamine receptorO77680DRD1Macaca mulatta (Rhesus macaque)446
146676Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
146686Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
146680Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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