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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL226227
Molecular formula	C35H47FN4
IUPAC name	1-[1-(4-fluorophenyl)-2-[4-[3-(2-methyl-6-phenylphenyl)propyl]piperazin-1-yl]ethyl]-4-propan-2-ylpiperazine
Molecular weight	542.787
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	6.7
Synonyms	(+/-)-1-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]-4-[3-(3-methylbiphenyl-2-yl)propyl]piperazine BDBM50202933
Inchi Key	JBXYADWMJLOTTL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H47FN4/c1-28(2)39-23-25-40(26-24-39)35(31-14-16-32(36)17-15-31)27-38-21-19-37(20-22-38)18-8-13-33-29(3)9-7-12-34(33)30-10-5-4-6-11-30/h4-7,9-12,14-17,28,35H,8,13,18-27H2,1-3H3
PubChem CID	44423459
ChEMBL	CHEMBL226227
IUPHAR	N/A
BindingDB	50202933
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
147157	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
147155	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
147154	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
147158	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
147156	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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