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Ligand

NameCHEMBL46527
Molecular formulaC8H11NO4
IUPAC name(1R,2S,4R,5R)-2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Molecular weight185.179
Hydrogen bond acceptor5
Hydrogen bond donor3
XlogP-3.2
SynonymsBDBM50064246
(1R,4R)-2beta-Aminobicyclo[2.1.1]hexane-2,5beta-dicarboxylic acid
(1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Inchi KeyJCGJEPFYMOHIDP-DJSMDIAISA-N
Inchi IDInChI=1S/C8H11NO4/c9-8(7(12)13)2-3-1-4(8)5(3)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8+/m1/s1
PubChem CID10775369
ChEMBLCHEMBL46527
IUPHARN/A
BindingDB50064246
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
147374Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
147375Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
147372Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
147371Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
147373Metabotropic glutamate receptor 6O15303GRM6Homo sapiens (Human)877

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