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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL296054
Molecular formula	C8H11NO4
IUPAC name	(1S,2S,4S,5S)-2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Molecular weight	185.179
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-3.2
Synonyms	Bicyclo[2.1.1]hexane-2,5-dicarboxylic acid, 2-amino-, (1S,2S,4S,5S)- (1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid CTK0J8288 ABHxD-I 208842-24-4 DTXSID50445745 BDBM50064248 [ Show all ]
Inchi Key	JCGJEPFYMOHIDP-RGDLXGNYSA-N
Inchi ID	InChI=1S/C8H11NO4/c9-8(7(12)13)2-3-1-4(8)5(3)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8-/m0/s1
PubChem CID	10846649
ChEMBL	CHEMBL296054
IUPHAR	N/A
BindingDB	50064248
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
147382	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
147384	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
147383	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
147385	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
147386	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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