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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL493573
Molecular formula	C19H17N3O2
IUPAC name	5-(2-methoxyphenyl)-N-(6-methylpyridin-2-yl)pyridine-3-carboxamide
Molecular weight	319.364
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50258375 5-(2-methoxyphenyl)-N-(6-methylpyridin-2-yl)nicotinamide
Inchi Key	JHJRKIXDTOTLFA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17N3O2/c1-13-6-5-9-18(21-13)22-19(23)15-10-14(11-20-12-15)16-7-3-4-8-17(16)24-2/h3-12H,1-2H3,(H,21,22,23)
PubChem CID	44157177
ChEMBL	CHEMBL493573
IUPHAR	N/A
BindingDB	50258375
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
151079	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
151080	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
151081	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
151082	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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